Medical microwave sterilization and drying equipment meets GMP certification of pharmaceutical enterprises

- May 08, 2019 -

Henan Microwave Equipment Network News: Since the national promulgation of GMP certification of drugs, many pharmaceutical enterprises need to be certified by the State Food and Drug Administration. For drug GMP certification and inspection items, articles 3101 to 3702 on equipment mainly focus on the hygiene and sterilization of pharmaceutical process. Medical microwave drying equipment can effectively solve the hygienic problems in the process of medical drying and sterilization.

P>Traditional medical sterilization requires pressure. At 120 C, holding for 20 to 40 minutes will destroy the pharmacodynamics and nutrients of the drug to a certain extent. In order to solve this problem, microwave drying sterilization equipment came into being. Microwave equipment in the pharmaceutical industry is mainly used in drying and sterilizing of pills, tablets, powder, granules, extracts of traditional Chinese medicine, extracts and various oral liquids, Chinese and Western medicines, and rapid extraction equipment of traditional Chinese medicine. The advantages of microwave sterilization and drying equipment are as follows:

P>1, short time and fast speed: conventional thermal sterilization transfers heat from food surface to interior through heat conduction, convection or radiation, and it often takes a long time to reach sterilization temperature. Microwave sterilization is a direct interaction between microwave energy and microorganisms such as food and bacteria. Thermal and non-thermal effects work together to achieve the purpose of rapid heating sterilization. The processing time is greatly shortened. The sterilization of various materials is generally 3-5 minutes.

2. Low temperature sterilization keeps nutrient composition and traditional flavor: Microwave sterilization is sterilized by special thermal and non-thermal effects. Compared with conventional thermal sterilization, microwave sterilization can obtain the required sterilization effect at lower temperature and in shorter time. Generally, the sterilization temperature is 75-80 degrees Celsius, which can achieve the effect. In addition, microwave treatment of food can retain more nutrients, color, fragrance, taste, shape and other flavors, and has puffing effect. For example, vitamin C of vegetables treated by conventional heating is 46% - 50%, while that of microwave heating is 60% - 90%. The vitamin A retention rate of porcine liver heated by conventional heating is 58%, while that of microwave heating is 84%. Energy saving: Conventional thermal sterilization often results in heat loss in environment and equipment, while microwave directly acts on food, so there is no additional heat loss. Generally speaking, it can save 30% to 50% of electricity.

4, easy to control: microwave dry sterilization treatment, equipment can be ready to use, no conventional thermal sterilization thermal inertia, flexible and convenient operation, microwave power can be adjusted, transmission speed can be continuously adjusted from zero, easy to operate.

5. Simple equipment and advanced technology: Compared with conventional methods, microwave equipment does not need boilers, complex pipeline systems, coal yards and transport vehicles, as long as it has basic water and electricity conditions. With the development of the pharmaceutical industry, the requirements for pharmaceutical sterilization machinery are becoming higher and higher. The microwave drying equipment for pharmaceutical sterilization meets the requirements of GM P and promotes the development of the pharmaceutical industry. In the future, pharmaceutical enterprises should maintain their advantages and continue to strengthen the innovation and transformation of pharmaceutical equipment.

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